|
In biochemistry and metabolism, beta-oxidation is the catabolic process by which fatty acid molecules are broken down in the mitochondria to generate acetyl-CoA, which enters the citric acid cycle, and NADH and FADH2, which are co-enzymes used in the electron transport chain. It is named as such because the beta carbon of the fatty acid undergoes oxidation to a carbonyl group. Various mechanisms have evolved to handle the large variety of fatty acids. ==Overview== Fatty acid catabolism consists of: #Activation and membrane transport of free fatty acids by binding to coenzyme A. #Oxidation of the beta carbon to a carbonyl group. #Cleavage of two-carbon segments resulting in acetyl-CoA. #Oxidation of acetyl-CoA to carbon dioxide in the citric acid cycle. #Electron transfer from electron carriers to the electron transfer chain in oxidative phosphorylation. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Beta oxidation」の詳細全文を読む スポンサード リンク
|